Marinka Zitnik

Fusing bits and DNA

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Nature Communications: General Method to Denoise Biological Networks

Technical noise in experiments is unavoidable, but it introduces inaccuracies into the biological networks we infer from the data.

In this Nature Communications paper, we introduce a diffusion-based method for denoising undirected, weighted networks, and show that it improves the performances of downstream analyses, including prediction of gene functions, interpretation of noisy Hi-C contact maps, and fine-grained identification of species.